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產品展示您現在的位置: 首頁 > 產品展示 > 美國戴安Dionex > 戴安液相色譜柱 > 美國戴安 P/N: 071387Dionex Acclaim Trinity P1 Series 液相色譜柱

Dionex Acclaim Trinity P1 Series 液相色譜柱

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型號 美國戴安 P/N: 071387
廠商性質 代理商
更新日期 2020-07-14

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

  • Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
  • Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
  • Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
  • Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

  • Active pharmaceutical ingredients (API) and counterions (cations or anions)
  • Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
  • Mixture of acidic and basic drug substances and respective counterions
  • Drug substances of acidic, basic, and neutral mixtures
  • High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技術參數：

 

Acclaim Trinity P1 Column – Superior Performance for Pharmaceutical Applications Specifications
Column chemistry SCX, WAX and RP Mixed-Mode
Operating pressure limit (recommended) 4500 psi (4000 psi)
Operating pH range (recommended) 2.5 – 7.0 (3.0 to 6.2)
Operating flow rate range (recommended) 0.3 – 1.5(0.4 – 0.8) mL/min for 3.0-mm i.d. formats
0.15 – 0.80 (0.2 to 0.4) mL/min for 2.1-mm i.d. formats

訂購信息：

 

 

Analytical Columns
Acclaim Trinity P1, 3?m, 3.0 x 150mm 075563
Acclaim Trinity P1, 3?m Analytical, (3.0 x 100mm) 071387
Acclaim Trinity P1, 3?m Analytical, (3.0 x 50mm) 071388
Acclaim Trinity P1, 3?m, 2.1 x 150mm 075564
Acclaim Trinity P1, 3?m Analytical, (2.1 x 100mm) 071389
Acclaim Trinity P1, 3?m, 2.1 x 50mm 075565
Guard Columns
Acclaim Trinity P1, 3?m Guard Cartridges, (3.0 x 10mm), 2ea (Use Holder V-2) 071390
Acclaim Trinity P1, 3?m Guard Cartridges, (2.1 x 10mm), 2ea (Use Holder V-2) 071391
Acclaim SST Guard Cartridge Holder V-2 069580
Acclaim Guard Kit (Holder and coupler) V-2 069707
Guard to Analytical Column Coupler V-2 074188

 

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